Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Cari Friedrich Hindenburg (1741-1808), le fondateur de la « prétendue Ecole combinatoire » (Eugen Netto), est un personnage largement oublié aujourd’hui. Pourtant, le Dictionary of Scientific Biography lui consacre un article. Il est vrai que l’Ecole combinatoire eut un grand succès en Allemagne à la fin du 18ème siècle, mais seulement en Allemagne, puis elle tomba en discrédit.En fait, l’Ecole combinatoire ne se proposait rien moins que de fonder l’analyse — et si possible toutes les mathématiques — sur l’analyse combinatoire, (...) une nouvelle branche des mathématiques qui était la création de Hindenburg : la problématique des fondements était au cœur de cette tentative. (shrink)

Transhumanism is a means of advocating a re-engineering of conditions that surround human existence at both ends. The problem set before us in this chapter is to inquire into what determined its appearance, in particular in the humanism it seeks to overcome. We look at the spirit of overcoming itself, and the impatience with the Self, in order to try to understand why it seeks a saving power in technology. We then consider how the evolutionary account of the production of (...) organisms does not set them against a perfect standard, but rather injects in them a contingency that seems to be near to the heart of the problem. We then try to assess the objective basis for improvements and manipulation of nature, and although we do not find it forbidden on all occasions, it seems that the criteria for such alterations are impossible to detach from a form of eugenics. We finally open a window toward a theological account of the problem, and find that the desire of autonomy and independence is inevitably going to be challenged by the Christian dogma of creation. (shrink)

This chapter compares Lotze’s, Lipps’, and Voigtländer’s notion of feelings of self-worth in order to carve out the specific and genuine aspects of Voigtländer’s understanding of self-feeling, as developed in her dissertation. Three lines of thinking important to her approach to the constitution of self-feeling are identified. While primarily sitting on an axis that stretches from the post-romantic Lotze via the descriptive psychologist Lipps to what is later understood as phenomenological philosophy, traces of two other major traditions can be discovered (...) in her proposal: (a) romantic psychology of the unconscious as found, for instance, in C. G. Carus, and (b), Nietzsche’s genealogical psychology of value. Both these traditions would later inspire biologistic versions of German Lebensphilosophie. By relying on them, it is argued, Voigtländer’s notion of self-feeling shows affinities with those vitalist approaches that fueled racist and eugenic ideologies in National Socialism. Given this, her theory of self-feeling in her dissertation from 1910 turns out to be fairly compatible with her later engagement in the fields of eugenics and membership in the NSDAP. Although her account of self-feeling is unique and interesting, therefore, it is finally suggested that Voigtländer’s proposal should be read with due caution. (shrink)

Ce volume rassemble pour l’essentiel les contributions d’un colloque organisé à l’université de Södertörn (Suède) en 2006. Dans leur introduction, les éditrices, J. Bornemark et M. Sà Cavalcante Schuback, rappellent l’importance et la diversité des travaux que des phénoménologues comme Max Scheler, Ortega y Gasset, Eugen Fink, Simone de Beauvoir, Ludwig Binswanger ainsi qu’Emmanuel Levinas et Jean-Luc Marion ont implicitement ou explicitement consacré au phénomène érotique. Comment la phénomé...

The author explores various pedagogical methods concerning how to teach Wittgenstein’s later work. A significant obstacle for the incorporation of Wittgenstein into an undergraduate curriculum is to decipher the major features of his philosophical ideas. The engagement with Wittgenstein’s work is not a task of mere comprehension or thought, but rather of discernment and observation of the ways language operates in the formulation of ideas. The distinction between observation and thought in Wittgenstein’s work on language is often overlooked. In order (...) to teach Wittgenstein effectively, the curriculum should focus on various methods to teach students not just to think but to observe. The author offers a series of classroom exercises and games to engage students with the text and to elucidate philosophical components necessary to understand the author. The games direct students’ attention to what they need to notice and observe in the function of language in Wittgenstein’s later work. (shrink)

The morbidity of tick‐borne encephalitis (TBE) varies yearly by as much as 10‐fold among the people of Western Siberia. This long‐term variation is dependent on many factors such as the density of the tick populations, the prevalence of TBE virus (TBEV) among sub‐adult ticks, the yearly virulence of the TBEV, and prophylactic measures. Here we highlight the role of small mammal hosts in the circulation of TBEV through the ecosystem. Refining classical models of non‐viremic horizontal transmission, we emphasize the recently (...) understood fact that the physiological and immunological status of the small mammal hosts affects the tick and virus‐host interactions. In addition to its theoretical interest, our approach may lead to some practical improvements in the precision of epidemiological forecasts and perhaps in forestalling the severity of outbreaks of TBE, or, at least, in forewarning medical authorities and the general public of impending TBE outbreaks. (shrink)

The possible existence of extraterrestrials has provoked more than five centuries of theological speculation on how these beings, if they exist, relate to God. A certain stream of thought present in these debates argues that the eventual discovery of aliens would obligate human Christians to evangelize them for the salvation of their souls. Current research into humanity's prehistory suggests that, if this ever actually happens, it will have been partially facilitated by humanity's remarkable capacity for interspecies empathy—an ability that seems (...) to be genetic in nature and which stems from our species' ancient experience with dogs. In light of the above, recommendations are made concerning future potential exomissionary screening criteria and a concluding section touches on the role of animals in God's work. (shrink)

Since Aristotle it is recognised that a valid syllogism cannot have two particular premises. However, that is not how a lay person sees it; at least as long as the premises read many, most etc, instead of a plain some. The lay people are right if one considers that these syllogisms do not have strict but approximate (Zadeh) validity. Typically there are only particular premises available in everyday life and one is dependent on such syllogisms. – Some rules on the (...) usage of particular premises are given below. (shrink)

This article is a critique of the failure of Wagner's Der Ring des Nibelungen. It considers this as a metaphysical problem rather than an aesthetic or formal one. The article, considering Wagner’s inheritance from Haydn, claims him as the first composer of the culture industry. This will lead the author to conclusions regarding a gendered Das Unheimlich, the distinction between technology and technique, and the philosophy of aesthetics.

The article investigates the interplay of moral rules in computer simulation. The investigation is based on two situations which are well-known to game theory: the prisoner''s dilemma and the game of Chicken. The prisoner''s dilemma can be taken to represent contractual situations, the game of Chicken represents a competitive situation on the one hand and the provision for a common good on the other. Unlike the rules usually used in game theory, each player knows the other''s strategy. In that way, (...) ever higher levels of reflection are reached reciprocally. Such strategies can be interpreted as moral rules.Artificial morality is related to the discipline of Artificial Life. As in artificial life, the use of genetic algorithms suggests itself. Rules of behaviour split and reunite as chromosome strings do. (shrink)

I argue that influential recent discussions have whitewashed blame, characterizing it in ways that deemphasize or ignore its morally problematic features. I distinguish “definitional,” “creeping,” and “emphasis” whitewash, and argue that they play a central role in overall endorsements of blame by T.M. Scanlon, George Sher, and Miranda Fricker. In particular, these endorsements treat blame as appropriate by definition (Scanlon), or as little more than a wish (Sher), and infer from blame's having one useful function that it is a good (...) practice overall (Fricker). I use an analogy with revenge to illustrate the mechanisms of whitewashing, including broadening a concept to include available alternatives to it and inference from one feature of a practice to an overall conclusion about that practice. Several features of blame make it particularly prone to whitewashing, including blamers' personal or emotional stake in blaming and widespread disagreement about the nature of blame. I argue that a non‐whitewashing treatment of blame must pay closer attention both to blame's harms, and to comparisons between blame and alternative, non‐blaming reactions. (shrink)

What is the good life? Posing this question today would likely elicit very different answers. Some might say that the good life means doing good—improving one’s community and the lives of others. Others might respond that it means doing well—cultivating one’s own abilities in a meaningful way. But for Aristotle these two distinct ideas—doing good and doing well—were one and the same and could be realized in a single life. In Confronting Aristotle’s Ethics, Eugene Garver examines how we can (...) draw this conclusion from Aristotle's works, while also studying how this conception of the good life relates to contemporary ideas ofmorality. The key to Aristotle’s views on ethics, argues Garver, lies in the Metaphysics or, more specifically, in his thoughts on activities, actions, and capacities . For Aristotle, Garver shows, it is only possible to be truly active when acting for the common good, and it is only possible to be truly happy when active to the extent of one’s own powers. But does this mean we should aspire to Aristotle’s impossibly demanding vision of the good life? In a word, no. Garver stresses the enormous gap between life in Aristotle’s time and ours. As a result, this book will be a welcome rumination on not only Aristotle, but the relationship between the individual and society in everyday life. (shrink)

The wide variety of blame presents two difficult puzzles. Why are instances of blame categorized under so many different mental kinds, such as judgment, belief, emotion, action, intention, desire, and combinations of these? Why is “blame” used to describe both interpersonal reactions and mere causal attributions, such as blaming faulty brakes for a car crash? I introduce a new conception of blame, on which blame is attention to something as a source of badness. I argue that this view resolves both (...) puzzles and offers an independently appealing conception of blame. (shrink)

Empirical evidence shows that people have multiple time-biases. One is near-bias, another is future-bias, and a third is present-bias. Philosophers are concerned with the normative status of these time-biases. They have argued that, at least in part, the normative status of these biases depends on the extent to which they tend to promote, or frustrate, wellbeing, where “wellbeing” is taken to be of fundamental value. Since near-bias is thought to be associated with impulsivity, lack of self-control, and poor long-term health (...) and financial outcomes, it has often been supposed that it is associated with lower wellbeing. On those grounds, philosophers have argued that near-bias is rationally impermissible. By contrast, philosophical views about the normative status of future-bias have been mixed, with some arguing that future-bias is impermissible because, they think, it frustrates wellbeing, and others arguing that it is at least permissible (and perhaps obligatory) because it is the product of mechanisms whose functioning can be expected to promote wellbeing. However, to date there are no studies that have directly probed how time-biases correlate with wellbeing. Since it's not a settled matter which psychological mechanisms underlie time-biases, it is not uncontroversial which things serve as proxies for these preferences. We directly empirically investigate the connection between time-biases and measures of wellbeing, to see which of these biases is associated with promoting, or frustrating wellbeing. Contrary to expectation, we found no evidence that near-bias or present-bias are associated with frustrating wellbeing on any of the constructs we measured. On the other hand, and contrary to what some philosophers have supposed, we found that future-bias was associated with higher measures of wellbeing on several measures. We consider the implications of these findings for the evaluation of the normative status of these time biases. (shrink)

Professional environmental ethics arose directly out of the interest in the environment created by Earth Day in 1970. At that time many environmentalists, primarily because they had read Aldo Leopold’s essay, “The Land Ethic,” were convinced that the foundations of environmental problems were philosophical. Moreover, these environmentalists were dissatisfied with the instrumental arguments based on human use and benefit—which they felt compelled to invoke in defense of nature—because they thought these arguments were part of the problem. Wanting to counter instrumental (...) arguments in some way with non- or even anti-instrumental arguments, and unable to think of anything else to say, they began wistfully suggesting that perhaps nature had or ought to have rights. When professional environmental ethics came into its own in the early 1980s, rights for nature were one of the first subjects to be debated in detail. Unfortunately, however, no one could come up with a theory to support such rights attributions. Nevertheless, because rights had been invoked by environmentalists to challenge the preeminent role of instrumental value arguments, and because the field of environmental ethics developed in support of environmental concerns and arguments, environmental ethicists turned to an examination of noninstrumental or intrinsic value arguments for the preservation of nature. (shrink)

Preparing general relativity for quantization in the Hamiltonian approach leads to the `problem of time,' rendering the world fundamentally timeless. One proposed solution is the `thermal time hypothesis,' which defines time in terms of states representing systems in thermal equilibrium. On this view, time is supposed to emerge thermodynamically even in a fundamentally timeless context. Here, I develop the worry that the thermal time hypothesis requires dynamics -- and hence time -- to get off the ground, thereby running into worries (...) of circularity. (shrink)

A number of philosophers claim that realism about dark matter in cosmology is unwarranted because there has been no empirical confirmation of a dark matter particle. This demand is misguided. I argue that we should take the theoretical concept of dark matter as described in our best cosmological model (ΛCDM) at face value. Since there is no theoretical or nomological requirement that dark matter be a particle, we should better assess the implications of dark matter detection via gravitational lensing. The (...) result is that realism about dark matter is a viable position. (shrink)

Taking the formal analogies between black holes and classical thermodynamics seriously seems to first require that classical thermodynamics applies in relativistic regimes. Yet, by scrutinizing how classical temperature is extended into special relativity, I argue that the concept falls apart. I examine four consilient procedures for establishing the classical temperature: the Carnot process, the thermometer, kinetic theory, and black-body radiation. I argue that their relativistic counterparts demonstrate no such consilience in defining the relativistic temperature. As such, classical temperature doesn’t appear (...) to survive a relativistic extension. I suggest two interpretations for this situation: eliminativism akin to simultaneity, or pluralism akin to rotation. (shrink)

Organizational misconduct (white collar, corporate and occupational crime, unethical behavior, rule violations, etc.) is an increasingly important social concern. This paper proposes that a necessary step toward preventing and treating such misconduct is the understanding of the explanations, called accounts, given by the actor. We argue that the theorizing and findings in the literature on accounts can be organized into a 2×2 matrix framework. The first dimension centers on whether or not the actor admits that some net harm is done (...) by the act, and the second consists of whether or not the actor admits responsibility. When both are admitted (cell 1), the account is a concession, while denial of both constitutes a refusal (cell 4). Admitting responsibility but not harm equates to a justification (cell 2), and the opposite condition is an excuse (cell 3). Building on this matrix, we specify a typology of explanations within each cell which will highlight inter-cell differences. Finally, we explore the implications of this analysis for managers, regulators, and the public. (shrink)

The reconciliation of theories of concepts based on prototypes, exemplars, and theory-like structures is a longstanding problem in cognitive science. In response to this problem, researchers have recently tended to adopt either hybrid theories that combine various kinds of representational structure, or eliminative theories that replace concepts with a more finely grained taxonomy of mental representations. In this paper, we describe an alternative approach involving a single class of mental representations called “semantic pointers.” Semantic pointers are symbol-like representations that result (...) from the compression and recursive binding of perceptual, lexical, and motor representations, effectively integrating traditional connectionist and symbolic approaches. We present a computational model using semantic pointers that replicates experimental data from categorization studies involving each prior paradigm. We argue that a framework involving semantic pointers can provide a unified account of conceptual phenomena, and we compare our framework to existing alternatives in accounting for the scope, content, recursive combination, and neural implementation of concepts. (shrink)

At the turn of the twentieth century, William James was America's most widely read philosopher. In addition to being one of the founders of pragmatism, however, he was also a leading psychologist and author of the seminal work, The Principles of Psychology. While scholars argue that James withdrew from the study of psychology after 1890, Eugene Taylor demonstrates convincingly that James remained preeminently a psychologist until his death in 1910.Taylor details James's contributions to experimental psychopathology, psychical research, and the (...) psychology of religion. Moreover, Taylor's work shows that out of his scientific study of consciousness, James formulated a sophisticated metaphysics of radical empiricism. In light of historical developments in psychology, as well as the current philosophic implications of the neuroscience revolution related to the biology of consciousness, Taylor argues that both the subject matter of James's investigations and his metaphysics of radical empiricism are just as important for psychology today as James believed they were in his own time.This book represents a major new contribution both to James scholarship and to the history of American psychology. Although philosophers have analyzed radical empiricism, this book is the first to trace the development of radical empiricism as a metaphysics addressed to psychologists. It is also the first to show James's involvement in depth-psychology and psychotherapeutics and to trace historical continuity between James's work on consciousness and subsequent developments in psychoanalysis, personality theory, and humanistic psychology. (shrink)

We blame faulty brakes for a car crash, or rain for our bad mood. This “merely causal” blame is usually seen as uninteresting. I argue that it is crucial for understanding the interpersonal blame with which we target ourselves and each other. The two are often difficult to distinguish, in a way that plagues philosophical discussions of blame. And interpersonal blame is distinctive, I argue, partly in its causal focus: its attention to a person as cause. I argue that this (...) causal focus helps explain several central characteristics of interpersonal blame: its tendency to exaggerate a person’s causal role, its weakening through attention to personal history or thoughts about determinism, its characteristic ‘force’ or ‘sting’, and our sense that blame is often harmful or unfair. I conclude by drawing out one implication of blame's causal focus: in a certain range of cases, blame is partly under our voluntary control. (shrink)

Akratic belief, or belief one believes one should not have, has often been thought to be impossible. I argue that the possibility of akratic belief should be accepted as a pre-theoretical datum. I distinguish intuitive, defensive, systematic, and diagnostic ways of arguing for this view, and offer an argument that combines them. After offering intuitive examples of akratic belief, I defend those examples against a common argument against the possibility of akratic belief, which I call the Nullification Argument. I then (...) offer an Argument from Belief Attribution, using a discussion of the marks by which we typically attribute belief to defend attributions of akratic belief. I conclude by offering a way to explain what is puzzling about akratic belief, while allowing that it is possible. (shrink)

The concept of business ethics has continued to remain a major item on the agenda of corporate America for the last twenty years. Regrettably, this longevity of interest has not been matched by equal attention to the pedagogical methods and techniques used to address these issues. The current mode of teaching business ethics generally involves reliance on “war stories,” case studies, andseminars. Today’s dynamic environment creates pressures for higher levels of ethical behavior by business. Many ethical challenges faced by contemporary (...) managers are not easily resolved by existing guidelines, and require managers to expand their scope of analysis in attempting to arrive at satisfactory resolutions. Literature can be an especially alternative source of insights, as authors are able to highlight behaviors that may not be available from traditional sources. Historically, the use of literature in examining business ethics has been focused primarily on novels such as The Jungle, Babbit, and The Great Gatsby. Plays are more useful than novels in attempting to inculcate moral and ethical values since they more sharply address the interactions of characters, and the reader becomes more involved in their situations. The plays selected for analysis, Henrik Ibsen’s An Enemy of the People, Arthur Miller’s Death of a Salesman, and David Mamet’s Glengarry Glen Ross, have intense plots and characters and allow the reader to observe a wide range motives, emotions, and traits. This untraditional approach to teaching business ethics enhances the ability to relate to the increasingly complex ethical issues facing the individual and the organization. (shrink)

The present discussion arose from the desire to explain, to an audience of non-physicists, the epistemology to which one is forced if one pursues the quantum mechanical theory of observation to its ultimate consequences. However, the conclusions will not be derived from the aforementioned theory but obtained on the basis of a rather general analysis of what we mean by real. Quantum theory will form the background but not the basis for the analysis. The concept of the real to be (...) arrived at shows considerable similarity to that of the idealist. As the title indicates, it is formulated as a dualism. It is quite possible that it will soon be rejected not only by the community of the philosophers but also by that of the scientists. If this should be the case, the attempt to derive an epistemology from physics will prove to have been premature. Naturally, the author hopes that this will not be the case because, quite apart from the quantum theoretical background, the concepts to be presented appear natural also as an outgrowth of common sense considerations. They have been arrived at by many who did not accept the epistemology of quantum mechanics. (shrink)

In Nuu-chah-nulth, the word tsawalk means "one." It expresses the view that all living things - humans, plants, and animals - form part of an integrated whole brought into harmony through constant negotiation and mutual respect for the other. Contemporary environmental and political crises, however, reflect a world out of balance, a world in which Western approaches for sustainable living are not working. In Principles of Tsawalk, hereditary chief Umeek builds upon his previous book, Tsawalk: A Nuu-chah-nulth Worldview, to elaborate (...) an alternative framework for responding to global environmental and political crises and to indigenous peoples' poverty, dispossession, and displacement in the realms of education and politics. These problems, Umeek argues, stem from an historical and persistent failure to treat all peoples and life forms with respect and accord them constitutional recognition. By contrast, the Nuu-chah-nulth principles of recognition, consent, and continuity, embodied in songs, language, and ceremonies, hold the promise of achieving sustainable lifeways in this shared struggle for balance. By weaving together Nuu-chah-nulth and Western worldviews, hereditary chief Umeek creates a new philosophical foundation for building more equitable and sustainable communities. Umeek (E. Richard Atleo), a hereditary Nuu-chah-nulth chief, is a research liaison at the University of Manitoba and an associate adjunct professor at the University of Victoria. He is the author of Tsawalk: A Nuu-chah-nulth Worldview. (shrink)

Conventional wisdom holds that the von Neumann entropy corresponds to thermodynamic entropy, but Hemmo and Shenker (2006) have recently argued against this view by attacking von Neumann's (1955) argument. I argue that Hemmo and Shenker's arguments fail due to several misunderstandings: about statistical-mechanical and thermodynamic domains of applicability, about the nature of mixed states, and about the role of approximations in physics. As a result, their arguments fail in all cases: in the single-particle case, the finite particles case, and the (...) infinite particles case. (shrink)